產品資訊 - Spironolactone/skype:sales05

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Spironolactone/skype:sales05_267

產品分類 :

化學->藥品->化學藥品

產品規格

Country	CN
Brand	yc
Size	1 miles
Weight	1
Color	white
Packing	10/bag
Minimum Order	10g
Payment Term	WU/GM/TT

產品描述

Spironolactone/skype sales05_267
Alias Aldactone Antisterone spirolactone
CAS NO 52-1-7
Einecs No 200-133-6
MF C24H32O4SMW 416 58
Purity 98
Grade Pharmaceutical Grade
Manufacturer QUANAO
Appearance White or white crystal powder of fine Slightly bitter taste odourless or slightly mercaptan odor.Insoluble in water soluble in ethanol soluble in benzene or ethyl acetate
Usage Spironolactone is competitive inhibition of aldosterone drugs drug itself is not active role is diuresis and endogenous competitive aldosterone antagonist and happen belongs to the potassium diuretics

Description

Spironolactone (INN BAN USAN) commonly referred to simply as spiro and marketed primarily under the brand name Aldactone in most countries is a synthetic steroide antimineralocorticoid and antiandrogen that also has some weak progestogen properties as well as some indirect estrogen and glucocorticoid effects It is used primarily as a diuretic and antihypertensive but may also be employed for the purpose of reducing elevated or unwanted androgen activity in the body It acts predominantly as an antagonist of the mineralocorticoid (or aldosterone) and androgen receptors and in relation to its antimineralocorticoid effects belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics

Application

Because spironolactone reduces the bodys production of testosterone and blocks the androgen receptors it can cause effects associated with low testosterone levels and hypogonadism in males For this reason men are typically not prescribed spironolactone for any longer than a short period of time eg for an acute exacerbation of heart failure The newer drug eplerenone has been approved by the U S Food and Drug Administration for treatment of heart failure but lacks the rather potent antiandrogen effects and thus is far more suitable for men for whom long term medication is being chosen. Unlike with some other diuretics potassium supplementation should not be administered while taking spironolactone as this may cause dangerous elevations in serum potassium levels resulting in hyperkalemia and potentially deadly cardiac arrythmias Physicians must be careful to monitor potassium levels in both males and females who are taking spironolactone especially during the first twelve months of use and whenever the dosage is increased

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